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Updated: Mar 22, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Audit and Feedback Supporting New Guideline Implementation in Chronic Kidney Disease
Megan E Lanpher1,2, Brooke Patterson1, Muhammad Ebrahim2
1College of Nursing, University of South Carolina, Columbia.
An audit and feedback intervention improved prescribing of sodium-glucose cotransporter-2 inhibitors (SGLT-2 inhibitors) for adults with Type 2 diabetes and chronic kidney disease. This intervention enhances adherence to clinical guidelines for delaying kidney disease progression.
Area of Science:
- Nephrology
- Endocrinology
- Clinical Quality Improvement
Background:
- Adults with Type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) face a high risk of progressing to end-stage kidney disease (ESKD).
- ESKD significantly impacts patient health, increases healthcare costs, and reduces quality of life.
- Sodium-glucose cotransporter-2 inhibitors (SGLT-2 inhibitors) are recommended to delay CKD progression in T2DM patients.
Purpose of the Study:
- To evaluate if an audit and feedback intervention can increase provider adherence to clinical practice guidelines for prescribing SGLT-2 inhibitors.
- To determine the effectiveness of this intervention in a local nephrology clinic setting.
Main Methods:
- A pretest-posttest design was employed over 3 months.
- Providers received audit and feedback at 3-week intervals, alongside a clinical decision guide.
- Participants included physicians and advanced practice providers from a southeastern US nephrology outpatient clinic.
Main Results:
- Statistical analysis showed a significant increase in SGLT-2 inhibitor prescriptions post-intervention.
- The intervention demonstrated a significant improvement in provider adherence to the guideline.
- Logistic regression confirmed the intervention's positive relationship with new SGLT-2 inhibitor prescriptions.
Conclusions:
- The audit and feedback intervention effectively increased SGLT-2 inhibitor prescribing in T2DM patients with CKD.
- Findings support the intervention's potential for broader implementation.
- Further research is needed to validate results and explore prescribing barriers.
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Chronic Kidney Disease I: Introduction
Chronic Kidney Disease II: Clinical Manifestations
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