First UK Experience Using LiNA OperaScope® for Botulinum Toxin Treatment under Local Anaesthesia in Women with...

Area of Science:

• Urology
• Gynecology
• Minimally Invasive Procedures

Background:

• Overactive bladder (OAB) significantly impacts women's quality of life.
• Current onabotulinum toxin A (Botox) treatments for OAB often require operating theatres and anesthesia.
• The LiNA OperaScope® presents a novel, less invasive outpatient method for Botox administration.

Purpose of the Study:

• To evaluate the feasibility and tolerability of the LiNA OperaScope® for OAB treatment in the UK.
• To compare patient-reported pain during LiNA OperaScope® procedures with prior cervical smear tests.
• To provide data for improved patient counseling regarding Botox injections for OAB.

Main Methods:

• Fifty women with OAB refractory to prior treatments received Botox injections using LiNA OperaScope®.
• Procedures were conducted in an outpatient setting under local anesthesia.
• Patient and surgeon feedback, including pain scores, was collected and compared to smear test experiences.

Main Results:

• The average pain score for the procedure was 2.2/10, with elderly patients reporting less pain.
• Patients experienced significantly less pain with LiNA OperaScope® than with cervical smear tests (p < 0.001).
• The average procedure time was under 3 minutes, with a low rate of manageable complications (e.g., UTIs).

Conclusions:

• LiNA OperaScope® is a feasible and well-tolerated option for outpatient Botox treatment of OAB in women.
• The procedure's low pain profile, comparable to smear tests, aids in patient counseling.
• This method offers a viable alternative to traditional operating room-based treatments.