[Comparative study of the sensitizing activity of heterologous serum preparations]

Experiments on guinea pigs and adrenalectomized mice showed that the anaphylactogenic properties xenogenic immunoglobulin preparations were 2- to 2.5-fold higher than those of antitoxic sera "Diaferm-3". The partial acid-enzymatic hydrolysis of immunoglobulin preparations obtained by ethanol fractionation permitted a considerable decrease in their sensitizing activity and anticomplementary properties.