T-Cell Prolymphocytic Leukaemia With Isolated Pulmonary Manifestation

Area of Science:

• Hematology
• Oncology
• Pulmonology

Background:

• T-cell prolymphocytic leukaemia (T-PLL) is a rare and aggressive hematologic malignancy.
• Pulmonary manifestations are uncommon in T-PLL, making diagnosis challenging.

Purpose of the Study:

• To report a unique case of T-PLL with isolated lung involvement.
• To emphasize the significance of pulmonary findings in T-PLL progression.

Main Methods:

• Case study of a T-PLL patient with exclusive lung infiltration.
• Diagnosis confirmed via video-assisted thoracoscopic surgery (VATS) biopsy.

Main Results:

• The patient presented with isolated pulmonary lesions.
• Histopathological analysis of the lung biopsy confirmed T-PLL infiltration.

Conclusions:

• Isolated lung infiltration in T-PLL can indicate advanced disease.
• Early detection and intervention are crucial for managing T-PLL with pulmonary spread.