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Exploring the Relationship Between Nonnutritive Sweeteners and Nutrient Intake: Findings from the ELSA-Brasil
Taiz Karla Brunetti Moreira1, Fernanda Duarte Mendes1, Hully Cantão Dos Santos2
1Post-Graduation Program in Nutrition and Health, Federal University of Espírito Santo, Vitória 29040-090, Brazil.
Nutrients
|June 13, 2025
Summary
Regular consumption of nonnutritive sweeteners (NNSs) was linked to lower daily calorie and carbohydrate intake in Brazilian adults. These findings suggest NNSs may aid in reducing overall caloric and sugar consumption.
Area of Science:
- Nutrition Science
- Dietary Assessment
- Public Health
Background:
- Nonnutritive sweeteners (NNSs) are widely used as sugar substitutes.
- Understanding the dietary impact of regular NNS consumption is crucial for public health.
- The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) provides a valuable dataset for this investigation.
Purpose of the Study:
- To investigate the association between regular nonnutritive sweetener (NNS) consumption and dietary intake patterns.
- To analyze the relationship between NNS use and energy, carbohydrate, and protein intake in a non-diabetic adult population.
- To assess the potential role of NNSs in modulating overall caloric and sugar intake.
Main Methods:
- Analysis of data from 9226 non-diabetic participants (aged 35-74 years) from the ELSA-Brasil baseline cohort.
- Definition of regular NNS consumption as daily use of NNS-sweetened products.
- Multivariate regression analysis adjusted for sociodemographic and lifestyle factors.
Main Results:
- Prevalence of regular NNS use was 25.7%, higher in women, older individuals, higher BMI categories, and higher socioeconomic status.
- Regular NNS consumption was significantly associated with reduced daily energy intake (-74.29 kcal).
- NNS use correlated with decreased total carbohydrate (-23.68 g) and simple carbohydrate (-11.24 g) intake, but increased protein (7.38 g) intake.
Conclusions:
- Regular nonnutritive sweetener (NNS) use is associated with lower caloric and carbohydrate intake, including sugars.
- While some nutrient compensation (carbohydrates/protein) may occur, the net effect suggests a reduction in overall energy and sugar consumption.
- NNSs may serve as a beneficial dietary tool for managing caloric and sugar intake in the general adult population.
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