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Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Socio-Demographic Risk Factors Associated with Diabetic Foot Ulcer in India: A Case Control Study
Nitesh Upadhyay1, Ajeet Saoji1, Prachi Saoji2
1Department of Community Medicine, NKP Salve Institute of Medical Sciences and Research Centre, Nagpur, Maharashtra, India.
Diabetic foot ulcers in India are linked to low socioeconomic status, rural living, and poor diabetes control. Addressing these factors is key to preventing DFU complications.
Area of Science:
- Public Health
- Epidemiology
- Diabetes Management
Background:
- Diabetic foot ulcers (DFU) are a major complication of diabetes mellitus, significantly impacting patient quality of life and straining healthcare systems, particularly in India.
- Understanding the socio-demographic factors associated with DFU is crucial for developing effective prevention strategies tailored to the Indian population.
Purpose of the Study:
- To identify socio-demographic and clinical risk factors associated with diabetic foot ulcers in the Indian population.
- To inform the development of targeted prevention and management strategies for DFU in India.
Main Methods:
- A case-control study was conducted in India over one year, involving 150 patients.
- Cases (75) had diabetic foot ulcers, while controls (75) were diabetic patients without foot ulcers.
- Data on socio-demographic variables, medical history, and lifestyle were collected via interviews and medical records, analyzed using logistic regression.
Main Results:
- Low socioeconomic status (OR=3.45), poor glycemic control (HbA1c >8%, OR=2.96), rural residence (OR=2.72), and lack of formal education (OR=2.30) were significantly associated with increased DFU risk.
- Additional risk factors included smoking, diabetes duration over 10 years, and a history of poor foot care practices.
Conclusions:
- Socioeconomic disparities and limited awareness of diabetic foot care significantly contribute to the burden of DFU in India.
- Targeted interventions, patient education, improved glycemic control, and accessible healthcare services are essential for managing this preventable complication.
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