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Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
Published on: May 6, 2013
Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity
Yahya A Almutawif1, Haydar M Al-Kuraishy2, Ali I Al-Gareeb3
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taibah University, Madinah, 42353, Saudi Arabia.
Abstract:
The current worldwide pandemic of monkeypox (MPXV) elicited apprehensions over its possible long-term health ramifications. Recent data indicate a potential association between MPXV infection and the onset of autoimmune disorders, such as type 1 diabetes (T1D). This article analyzes the possible methods for MPXV infection to induce autoimmune responses and damage pancreatic β-cells. We examine from published articles the possible MPXV-induced immune dysregulation and inflammation in the development of T1D. Utilizing insights from other diabetogenic viruses, such as enterovirus and SARS-CoV-2. Currently, the association between MPXV and the development of T1D is scarce. Therefore, additional studies are essential for establishing a conclusive causal link between MPXV and T1D.
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