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Related Experiment Video

Updated: Sep 19, 2025

Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses
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Pseudosocial cognition and paranoia.

Philip Corlett1, Rosa Rossi-Goldthorpe1, Praveen Suthaharan1

  • 1Yale University, New Haven, CT, USA.

Trends in Cognitive Sciences
|June 15, 2025
PubMed
Summary
This summary is machine-generated.

A simpler pseudosocial learning mechanism, not specialized social cognition, may explain persecutory delusions. This research focuses on prediction and association, offering new insights into delusion formation.

Keywords:
computational psychiatrydomain-generaldomain-specificparanoiapsychosis

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Area of Science:

  • Cognitive neuroscience
  • Psychiatry
  • Computational psychiatry

Background:

  • The "social turn" in delusions research posits specialized social cognition underlies persecutory delusions.
  • This perspective suggests paranoia involves coalitional cognition and reputation management.

Purpose of the Study:

  • To propose an alternative pseudosocial learning mechanism for persecutory delusions.
  • To contrast this mechanism with specialized social cognition in terms of computation, algorithm, and implementation.

Main Methods:

  • Computational modeling focusing on prediction and association.
  • Analysis of dopaminergic system involvement in domain-general learning.
  • Comparison with theories of social-specific cognitive mechanisms.

Main Results:

  • Pseudosocial learning, based on prediction and association, offers a simpler explanation for delusions.
  • Domain-general brain regions, particularly dopaminergic pathways, may underpin these learning processes.
  • Evidence suggests a simpler associative learning mechanism is more plausible than complex coalitional cognition.

Conclusions:

  • Persecutory delusions may arise from domain-general pseudosocial learning rather than specialized social cognitive mechanisms.
  • Future research should explore the interplay between domain-general and social-specific processes in delusion formation.
  • Adversarial collaboration is recommended to differentiate the roles of these cognitive systems.