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Comparison of Intradermal Versus Microneedling-Assisted Botulinum A Toxin Injection for Enlarged Facial Pores: A
Fariba Iraji1, Reza Moeini1, Mahya Abedini1
1Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.
Journal of Cosmetic Dermatology
|June 16, 2025
Summary
Both intradermal and microneedling-assisted Botulinum toxin type A injections effectively reduce enlarged facial pores. This study found no significant difference in efficacy between these two popular cosmetic treatments.
Area of Science:
- Dermatology
- Cosmetic Procedures
- Aesthetic Medicine
Background:
- Enlarged facial pores are a common cosmetic concern.
- Traditional treatments include topical agents and lasers.
- Intradermal and microneedling-assisted Botulinum toxin type A (BoNTA) injections are emerging alternatives.
Purpose of the Study:
- To compare the efficacy of intradermal versus microneedling-assisted BoNTA injections for reducing enlarged facial pores.
Main Methods:
- A randomized clinical trial involving 30 patients with enlarged facial pores.
- BoNTA was administered intradermally on one side of the face and via microneedling on the other.
- Evaluations included dermoscopy, physical examination, Quartile Improvement Scale (QIS), and Likert scale for patient satisfaction at baseline and 1 month post-treatment.
Main Results:
- No significant difference in pore size reduction was observed between intradermal and microneedling-assisted BoNTA injections on either cheek or nose areas (p > 0.05).
- Patient satisfaction scores were comparable between the two treatment modalities (p = 0.13).
- Both methods demonstrated effectiveness in reducing pore size.
Conclusions:
- Intradermal and microneedling-assisted BoNTA injections offer comparable efficacy for treating enlarged facial pores.
- The choice between these treatments can be based on dermatologist preference and patient considerations.
- Both techniques provide a viable option for improving pore size and patient satisfaction.
