[Physical mechanism of spatial organization in epithelial morphogenesis]

The morphogenetic movements of embryonic epithelia are preceded by their marking into motor active and passive zones. It is carried out as a result of spontaneous splitting of the epithelial layer to domains of morphologically polarized (motor active) and isotropic cells. Processes of the cellular level are dependent on the global supracellular organization. The mechanism of selforganization of macroscopic supracellular order in the course of cell polarization is analysed. A number of more elementary properties of the embryonic material inferred from the experiments proves to be sufficient for the initiation of such mechanism.