Related Experiment Video
Updated: Sep 19, 2025
10:10
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
1.5K
Neovascular Glaucoma With Persistent Epithelial Defect: Pathophysiology and Surgical Solutions.
Anugya Sharma1, Suneeta Dubey1
1Department of Glaucoma, Dr. Shroff's Charity Eye Hospital, New Delhi, IND.
Cureus
|June 17, 2025
Summary
This case study details managing a diabetic patient with severe neovascular glaucoma and ocular surface disease. Successful treatment involved amniotic membrane grafting and trabeculectomy, highlighting a tailored approach.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- A 55-year-old male diabetic patient presented with bilateral uncontrolled neovascular glaucoma.
- The patient also exhibited drug-related ocular surface toxicity, leading to persistent epithelial defects in both eyes.
Observation:
- Uncontrolled neovascular glaucoma and ocular surface toxicity presented a complex clinical challenge.
- Persistent epithelial defects indicated significant damage to the corneal surface.
Findings:
- Successful management of the first eye involved amniotic membrane grafting combined with trabeculectomy.
- A similar therapeutic strategy was employed for the second eye, achieving successful co-management.
Implications:
- This case underscores the necessity of individualized, comprehensive treatment plans for complex ophthalmic conditions.
- The combined approach of amniotic membrane grafting and glaucoma surgery offers a viable solution for managing severe ocular surface disease and neovascular glaucoma.
Related Concept Videos
01:25Glaucoma: Overview
792
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
792
01:28Angle Closure Glaucoma: Treatment
718
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
718
01:27Open Angle Glaucoma: Treatment
597
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
597