Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinic practitioner and support staff perspectives on implementation strategies to increase patient referrals to diabetes self-management education and support services.

Implementation science communications·2026
Same author

Ivermectin for Critically and Noncritically Ill Hospitalized Patients With COVID-19: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP).

Critical care medicine·2026
Same author

Wastewater Surveillance for SARS-CoV-2 in Rural Kentucky, 2021-2023.

Viruses·2026
Same author

Intermediate dose heparin thromboprophylaxis among critically ill patients with COVID-19: a randomized clinical trial.

Journal of thrombosis and haemostasis : JTH·2026
Same author

Nirsevimab is Effective Against Respiratory Syncytial Virus-Associated Hospitalization Among American Indian and Alaska Native Children in Their First and Second RSV Seasons in Alaska and the Southwest United States, 2023-2024: Erratum.

The Pediatric infectious disease journal·2026
Same author

Increasing Uptake of Diabetes Self-Management Education and Support (DSMES) in Rural Kentucky Primary Care Clinics: Findings From a Pilot Pragmatic Cluster-Randomized Trial.

Journal of primary care & community health·2026
Same journal

Biodegradable Self-Powered Electrotherapy Patch for Integrated Smart Wound Management.

Analytical chemistry·2026
Same journal

Metabolite Fraction Libraries for Quantitative NMR Metabolomics.

Analytical chemistry·2026
Same journal

Self-Contained Lateral-Flow Microfluidic Bead-Based Assay for Rapid Quantification of Early-Stage Kidney Biomarkers.

Analytical chemistry·2026
Same journal

Overcoming the Debye Shielding Effect with Concave-Convex Structures for Sensitivity-Enhanced Thin-Film Transistors.

Analytical chemistry·2026
Same journal

Mode-Phase-Difference Photothermal Spectroscopy Assisted by a Bent Biconically Tapered Microfiber for Gas Sensing.

Analytical chemistry·2026
Same journal

Negative-Pressure-Actuated Microfluidics: A Dual-Mode Point-of-Care Sensor for Allergen-Specific IgE in Interstitial Fluid.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: Jun 19, 2026

Microfluidic Chip Fabrication and Method to Detect Influenza
09:43

Microfluidic Chip Fabrication and Method to Detect Influenza

Published on: March 26, 2013

15.1K

Enabling SARS-CoV-2 Wastewater Surveillance Using an Integrated Microfluidic Chip.

Mohammad Dehghan Banadaki1, Soroosh Torabi1, William D Strike2

  • 1Department of Mechanical and Aerospace Engineering, College of Engineering, University of Kentucky, Lexington, KY 40506, United States.

Analytical Chemistry
|June 17, 2025
PubMed
Summary
This summary is machine-generated.

A new device simplifies infectious disease surveillance in wastewater, making wastewater-based epidemiology (WBE) accessible for low-resource areas. This affordable, user-friendly platform enables rapid pathogen detection at the point-of-use.

More Related Videos

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.0K
Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip
06:11

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

2.0K

Related Experiment Videos

Last Updated: Jun 19, 2026

Microfluidic Chip Fabrication and Method to Detect Influenza
09:43

Microfluidic Chip Fabrication and Method to Detect Influenza

Published on: March 26, 2013

15.1K
A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
15:41

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

15.0K
Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip
06:11

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

2.0K

Area of Science:

  • Environmental microbiology
  • Public health surveillance
  • Point-of-care diagnostics

Background:

  • Wastewater-based epidemiology (WBE) is a valuable tool for public health surveillance.
  • Implementation challenges in low-resource settings include infrastructure and expertise limitations.
  • Centralized laboratory dependence hinders rapid WBE deployment.

Purpose of the Study:

  • To develop and validate a novel, affordable, point-of-use device for WBE.
  • To integrate nucleic acid concentration, extraction, and detection into a single platform.
  • To overcome limitations of traditional WBE in resource-limited regions.

Main Methods:

  • A concentration-extraction-identification device (CEID) was developed.
  • Immiscible filtration assisted by surface tension (IFAST) for nucleic acid extraction.
  • Colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) for pathogen detection.

Main Results:

  • Optimized CEID demonstrated efficient nucleic acid extraction with minimal inhibition.
  • Achieved a SARS-CoV-2 detection limit of 113 Cp/mL in spiked wastewater.
  • Successfully detected SARS-CoV-2 in a 6-week wastewater surveillance study, correlating with RT-qPCR.

Conclusions:

  • The CEID is an affordable ($11/sample), user-friendly, and adaptable technology for WBE.
  • This platform democratizes WBE, enhancing infectious disease surveillance in underserved areas.
  • The CEID offers a scalable solution for global health security, especially in low- and middle-income countries.