Persistence of nocturia after BPH surgery: a multicenter study.

Area of Science:

• Urology
• Surgical Innovation
• Lower Urinary Tract Symptoms Research

Background:

• Nocturia is a common and distressing lower urinary tract symptom (LUTS) in men with benign prostatic obstruction (BPO).
• Endoscopic enucleation of the prostate (EEP) is a surgical option for BPO.
• The impact of EEP on nocturia requires further investigation.

Purpose of the Study:

• To assess the long-term outcomes of nocturia following EEP for LUTS/BPO.
• To identify predictors of persistent nocturia after EEP.

Main Methods:

• Multicenter retrospective study of 120 men undergoing EEP.
• Voiding diaries used for nocturia evaluation.
• Outcomes analyzed for remission, improvement, stability, and worsening.

Main Results:

• At 15 months median follow-up, 45% achieved complete nocturia remission, 19% partial improvement.
• Predominant overactive bladder symptoms were the sole significant predictor of no response (HR 1.68).
• No association found with age, BMI, prostate volume, or comorbidities.

Conclusions:

• EEP can lead to meaningful nocturia improvement in nearly two-thirds of men with LUTS/BPO.
• Nocturia persistence after EEP may be linked to overactive bladder.
• The multifactorial nature of nocturia should be considered post-surgery.