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Updated: Sep 18, 2025

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Enhancing Lung Cancer Diagnosis: An Optimization-Driven Deep Learning Approach with CT Imaging.

Kasetty Lakshminarasimha1, A T Priyeshkumar2, M Karthikeyan3

  • 1SVR Engineering College, Nandyal, India.

Cancer Investigation
|June 23, 2025
PubMed
Summary
This summary is machine-generated.

This study presents an optimized deep learning model for lung cancer detection using CT scans. The model achieves high accuracy, offering a promising tool for faster and more reliable diagnosis.

Keywords:
EfficientNetLung cancerattention mechanismbio-inspired optimizationcomputed tomography imagesperformance metrics

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Oncology

Background:

  • Lung cancer (LC) is a major global health concern, necessitating accurate and timely diagnosis.
  • Computed Tomography (CT) is crucial for LC detection, but manual analysis is labor-intensive and prone to errors.
  • Existing deep learning models struggle with feature extraction and computational complexity in high-dimensional CT data.

Purpose of the Study:

  • To develop an optimized deep learning model for enhanced lung cancer classification from CT images.
  • To improve feature extraction efficiency and reduce computational complexity in lung cancer detection.
  • To investigate the impact of various optimization algorithms on model performance.

Main Methods:

  • An optimized CBAM-EfficientNet model was developed, integrating EfficientNet for reduced complexity and CBAM for feature emphasis.
  • Gray Wolf Optimization (GWO), Whale Optimization (WO), and Bat Algorithm (BA) were employed for hyperparameter tuning.
  • The model was evaluated on the Lung-PET-CT-Dx and LIDC-IDRI benchmark datasets.

Main Results:

  • The GWO-based CBAM-EfficientNet achieved high accuracies: 99.81% on Lung-PET-CT-Dx and 99.25% on LIDC-IDRI.
  • The BA-based CBAM-EfficientNet demonstrated strong performance with 99.44% and 98.75% accuracy on the respective datasets.
  • The proposed model significantly outperformed existing methods in lung cancer classification.

Conclusions:

  • The optimized CBAM-EfficientNet model offers a highly accurate and efficient solution for automated lung cancer diagnosis.
  • The integration of optimization algorithms enhances predictive accuracy and model robustness.
  • The lightweight architecture facilitates real-time clinical application, aiding radiologists in diagnosis.