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Innovations and Emerging Therapies in Atopic Dermatitis Part 1
1Department of Dermatology, Oregon Health and Sciences University, 3303 S Bond Ave Building 1, 16th Floor, Portland, OR 97239, USA.
Purpose Of Review:
The purpose of this review is to discuss the innovative aspects of present and newer therapies used for the treatment of AD, as well as to highlight the characteristics of emerging treatments. We also compare alternative systemic therapies. The novelties surrounding systemic therapies will be highlighted in this first review (part 1), while innovations in topical therapies will be discussed in a subsequent review (part 2).
Recent Findings:
The treatment landscape of atopic dermatitis has been quickly evolving in recent history. The treatment framework of AD is shifting from broad suppression of the inflammatory response to targeted molecular therapy.
Summary:
Overall, this therapeutic shift does appear to correlate with a superior efficacy and safety profile, though we also highlight encountered shortcomings when assessing long-term and real-world data of systemic therapies. Despite significant recent advances, future studies are needed to optimize formulations and performance of systemic therapies for AD.
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