Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Cell Signaling01:23

Overview of Cell Signaling

21.4K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
21.4K
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

6.8K
The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
6.8K
Contact-dependent Signaling01:19

Contact-dependent Signaling

45.1K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
45.1K
Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

6.6K
Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
6.6K
What is Cell Signaling?02:03

What is Cell Signaling?

120.8K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
120.8K
Autocrine Signaling01:01

Autocrine Signaling

48.8K
Autocrine signaling is one of the many signaling mechanisms that function inside multicellular organisms to carry out intercellular communication. In this type of signaling mechanism, the same cell that secretes an extracellular signaling molecule also expresses the receptors to bind and respond to that signaling molecule.
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...
48.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stimulation success!? Improved response inhibition performance after prefrontal single-site and condition-and-perturb transcranial magnetic stimulation.

Cognitive, affective & behavioral neuroscience·2026
Same author

Spoiler alert: Reliable distractor response cues benefit response selection.

Journal of experimental psychology. Learning, memory, and cognition·2026
Same author

No error on the side of safety: No representational momentum for auditory looming stimuli.

Psychonomic bulletin & review·2026
Same author

The Touching Difference: Evidence for Stimulus-Response Binding Effects in Tactile Detection and Localization Performance but Not in Their Visual Counterparts.

Journal of cognition·2026
Same author

When affordances are not universal: The negative compatibility effect is modulated by task type and spatial association.

Attention, perception & psychophysics·2025
Same author

Habituation in Predictability-Modulations of Stimulus-Response Binding.

Journal of cognition·2025
Same journal

The effect of retrieval practice on incidental memory is modulated by emotional valence: evidence of ERPs.

Psychological research·2026
Same journal

The length of a piece of string: Where the whole is more than the sum of its constituent parts.

Psychological research·2026
Same journal

The influence of older age, individual differences in cognitive abilities, and state of mind on learning novel categories.

Psychological research·2026
Same journal

Effects of transcranial electrical stimulation on face identification and related perceptual processes: a systematic review.

Psychological research·2026
Same journal

Context-dependent motor-semantic interactions: evidence from dual-task paradigms in semantic fluency.

Psychological research·2026
Same journal

A dual-process account of metaphorical embodiment.

Psychological research·2026
See all related articles

Related Experiment Video

Updated: Sep 18, 2025

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.7K

Signaling as a context-dependent strategy in action control.

Lorena Hell1,2, Christoph Felix Geissler3, Philip Schmalbrock4,3

  • 1Department of Cognitive Psychology, Trier University, Universitätsring 15, Building D, 54296, Trier, Germany. hell@uni-trier.de.

Psychological Research
|June 23, 2025
PubMed
Summary
This summary is machine-generated.

Context influences decision-making strategies. This study found that the comparability of display set sizes affects how people adapt their response strategies, impacting performance in sequential tasks.

More Related Videos

New Variations for Strategy Set-shifting in the Rat
09:45

New Variations for Strategy Set-shifting in the Rat

Published on: January 23, 2017

8.3K
Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE
06:57

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE

Published on: May 14, 2019

10.6K

Related Experiment Videos

Last Updated: Sep 18, 2025

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.7K
New Variations for Strategy Set-shifting in the Rat
09:45

New Variations for Strategy Set-shifting in the Rat

Published on: January 23, 2017

8.3K
Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE
06:57

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE

Published on: May 14, 2019

10.6K

Area of Science:

  • Cognitive Psychology
  • Human-Computer Interaction

Background:

  • Sequential tasks often show partial repetition costs, where performance degrades if only stimulus or response repeats.
  • The signaling account suggests a heuristic uses stimulus relations to signal response repetition or change.

Purpose of the Study:

  • To investigate if contextual information, specifically display set size comparability, modulates the signaling heuristic.
  • To understand how environmental context influences response strategies in sequential decision-making.

Main Methods:

  • Participants completed sequential two-choice tasks with varying display set sizes.
  • Experiment 1 used within-participant variation of set sizes for direct comparison.
  • Experiment 2 used between-participant variation of set sizes, preventing direct comparison.

Main Results:

  • Partial repetition costs were absent with small set sizes and emerged at larger set sizes in Experiment 1.
  • Experiment 2 showed similar partial repetition costs across set sizes, regardless of comparability.
  • These findings indicate context-dependent adaptation of signaling heuristics.

Conclusions:

  • The signaling heuristic is not fixed but adapts based on contextual cues like display set size comparability.
  • Environmental context plays a crucial role in shaping cognitive strategies for response selection.