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Published on: February 2, 2017
[Association between feeding patterns within 4 months of age and physical growth, overweight and obesity in children
Zi Ye1, Yanan Kong1, Ji Min2
1National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Key Laboratory of Human Milk Science, Chinese Center for Disease Control and Prevention;NHC Key Laboratory of Public Nutrition and Health, Beijing 100050, China.
Insights
Infant feeding patterns within the first 4 months do not impact physical growth up to age 3. Overweight and obesity risks in young children are primarily linked to birth weight and delivery method, not early diet.
Area of Science:
- Pediatric nutrition
- Childhood growth and development
- Public health
Context:
- Prospective cohort study in China (TAWS) followed 1458 children from 2013-2019.
- Feeding patterns within the first 4 months were assessed via questionnaire.
- Physical growth (WAZ, LAZ, WLZ) and overweight/obesity risk were tracked up to 3 years of age.
Purpose:
- To examine the association between early infant feeding patterns (first 4 months) and physical growth.
- To determine the relationship between early feeding patterns and the risk of overweight and obesity in children aged 0-3 years.
Summary:
- No significant differences in length-for-age Z-score (LAZ), weight-for-length Z-score (WLZ), or weight-for-age Z-score (WAZ) were found among different feeding pattern groups.
- Early feeding patterns (within 4 months) were not associated with the risk of overweight and obesity after adjusting for confounding factors.
- High birth weight (large-for-gestational-age) and caesarean delivery were associated with a higher risk of overweight and obesity at 12 months.
Impact:
- Findings suggest that early feeding patterns have a limited role in long-term physical growth and weight status.
- Highlights the significant influence of prenatal factors (birth weight) and delivery mode on childhood overweight and obesity.
- Informs guidance on childhood obesity prevention, emphasizing factors beyond early infant feeding.
Objective:
To investigate the association between feeding patterns within 4 months of age and both physical growth and the risk of overweight and obesity in young children aged 0-3 years.
Methods:
Based on the TAWS prospective cohort study in China, children aged 0-3 years were followed up in Taicang cohort from 2013 to 2019. A structured questionnaire was used to collect and evaluate the feeding patterns of children within the first 4 months, weight and height/length were measured at birth and at 1, 3, 6, 8, 12, 18, 24, 30 and 36 months of age, weight for age Z-score(WAZ), length for age Z-score(LAZ) and weight for length Z-score(WLZ) were calculated for each measurement. The χ~2 test was used to compare the malnutrition rates, and applied ANOVA to analyze the differences in physical Z-scores among different feeding patterns at each measurement. Multivariate logistic regression was employed to analyze the correlation between feeding patterns and the risk of overweight and obesity.
Results:
Among 1458 children, 18.11%(n=264), 19.41%(n=283), 44.58%(n=650), 15.16%(n=221) and 1.65%(n=24) of them were exclusively breastfed, predominantly breastfed, mixed fed mainly on breast-milk, mixed fed mainly on formula, and formula fed. There were no differences in LAZ、WLZ and WAZ(except 3 months) among the different feeding pattern groups at each time point(P>0.05). After adjusting for the season of physical examination, birth weight, delivery mode, age at weaning, age at introduction of formula and complementary food, feeding patterns within the first 4 months were not associated with the risk of overweight and obesity. The risk of overweight and obesity in children under the age of 3 years was mainly associated with birth weight and delivery mode. Among them, at 12 months of age, the risk of overweight and obesity was higher in children with high birth weight(large-for-gestational-age) than children with normal birth weight(appropriate-for-gestational-age)(OR=4.14, 95% CI 2.06-8.32), and the risk of overweight and obesity was higher in children born by caesarean section than those born naturally(OR=2.47, 95% CI 1.06-8.32).
Conclusion:
Children's feeding patterns withinh 4 months are not associated with their physical growth in their first 3 years. Overweight and obesity are mainly influenced by birth weight and delivery mode.
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