Related Experiment Video
Updated: Sep 18, 2025

Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety
Published on: January 20, 2012
Treating a Case of Disgust-Based Contamination Obsessive-Compulsive Disorder Using a Functional Approach to Exposure
1Ithaca, NY, USA rsgassoc@gmail.com.
Abstract:
Research has shown that disgust-based contamination obsessive-compulsive disorder (OCD) is often challenging to treat due to neurological and behavioral differences that can inhibit short-term habituation. This article presents a case study of using a novel functional approach to exposure and response prevention for disgust-based OCD focused on facilitating practice in avoided situations, incorporating concepts from acceptance and commitment therapy as well as emerging literature on using judicious safety behaviors to enable repeated practice. This case involves a 39-year-old male patient with disgust-based contamination OCD treated using this approach. Following a short course of psychotherapy combined with self-directed practice, the patient's measured level of OCD severity (Yale-Brown Obsessive Compulsive Scale) was reduced by 56% over a 5-month period, with the patient meeting remission at posttreatment.
More Related Videos
Related Concept Videos
Obsessive-Compulsive Disorder
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Preparedness and Phobias
Binge Eating Disorders

