Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

30
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
30
Cardiopulmonary Resuscitation I: Adult01:21

Cardiopulmonary Resuscitation I: Adult

95
Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...
95
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

38
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
38
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

77
Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
77
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

81
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
81

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complex hybrid management of severe aortic stenosis and aortic arch disease in a nonagenarian: a case report.

European heart journal. Case reports·2026
Same author

Propensity-matched analysis of the impact of saphenous vein graft external stenting on clinical outcomes in coronary bypass surgery: The RESTART study.

JTCVS open·2025
Same author

Demonstration of a Mechanical External Biventricular Assist Device for Resuscitative Thoracotomy.

Cardiovascular engineering and technology·2025
Same author

Oncological outcomes of the first pulmonary artery trunk transplantation for thymic carcinoma: a reflective analysis of surgical radicality.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2025
Same author

Ascending aortic aneurysm and dissection risk: focus on aortic height index.

Interdisciplinary cardiovascular and thoracic surgery·2025
Same author

A very late intracardiac myxoid liposarcoma metastasis.

European heart journal. Cardiovascular Imaging·2024
Same journal

Erratum: Safety and Efficacy of Stored Wet-Preprimed Extracorporeal Membrane Oxygenation Circuits: A Scoping Review.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Case Series of Extracorporeal Cardiopulmonary Resuscitation for Refractory Cardiopulmonary Arrest After Cardiac Surgery.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Association Between Veno-Venous Extracorporeal Membrane Oxygenation and Right Ventricular Dysfunction in Acute Respiratory Distress Syndrome Patients: A Multicenter Retrospective Propensity-Matched Study.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Prolonged Mechanical Circulatory Support of Neonatal Biventricular Failure via Single Ventricle Conversion With Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Redefining Limits: Extracorporeal Cardiopulmonary Resuscitation in Adult Thrombotic Thrombocytopenic Purpura.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same journal

Blood Coagulation Analysis in Pediatric Patients on Extracorporeal Life Support with Small-Volume Acoustic Tweezing Thromboelastometry.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
See all related articles

Related Experiment Video

Updated: Sep 17, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.4K

Direct Cardiac Compression Device for Short-Term Mechanical Circulatory Support.

Kristof Sarosi1, Thomas Kummer1, Stijn Vandenberghe2,3

  • 1From the Institute of Fluid Dynamics, Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|June 27, 2025
PubMed
Summary
This summary is machine-generated.

A novel direct cardiac compression (DCC) patch offers mechanical circulatory support (MCS) without blood contact. This device shows comparable performance to open-chest cardiac compression in an ex vivo model.

Keywords:
cardiac arrestdirect cardiac compressionemergency heart surgerymechanical circulatory supportventricular assist device

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.7K
Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.0K

Related Experiment Videos

Last Updated: Sep 17, 2025

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.4K
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
07:39

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

3.7K
Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
07:41

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device

Published on: July 20, 2022

2.0K

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Medical Device Innovation

Background:

  • Current short-term ventricular assistance options are limited and invasive.
  • Existing mechanical circulatory support (MCS) devices interact with the bloodstream, posing risks.
  • Direct cardiac compression (DCC) offers a non-blood-contacting alternative for MCS.

Purpose of the Study:

  • To evaluate a novel DCC patch device for short-term MCS.
  • To compare the DCC patch device's performance against open-chest cardiac compression (OCCC).
  • To assess the DCC patch device's efficacy in an ex vivo ovine cardiac arrest model.

Main Methods:

  • Utilized an ex vivo ovine cardiac arrest (CA) heart model.
  • Compared a novel DCC patch device to open-chest cardiac compression (OCCC).
  • Evaluated device performance by measuring pressure, flow rate, and valve function, and assessing tissue damage.

Main Results:

  • The DCC patch device achieved a cardiac output of 1.5 L/min and a mean aortic pressure of 55 mm Hg.
  • Effective valve function was maintained despite direct epicardial contact.
  • The DCC patch device demonstrated performance comparable to OCCC.

Conclusions:

  • The novel DCC patch device shows potential for short-term mechanical circulatory support.
  • This non-invasive approach maintains hemodynamic function and valve integrity.
  • Results support the feasibility of DCC patch devices for various MCS applications.