Related Experiment Video
Updated: Sep 17, 2025
09:14
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
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Systematic Review: Convergence and Divergence Between Autism Spectrum Disorder and Obsessive-Compulsive Disorder:
Joseph A Pereira1, Jeremy Veenstra-VanderWeele2, Amandeep Jutla3
1Columbia University, New York, New York; Weill Cornell Medicine in New York, New York.
Summary
Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) share genetic links and some cognitive inflexibility. However, neuroimaging shows differences in cortical thickness, highlighting distinct patterns despite overlapping symptoms.
Area of Science:
- Neuroscience
- Genetics
- Psychiatry
Background:
- Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) are distinct diagnoses with overlapping presentations and frequent co-occurrence.
- The precise relationship between ASD and OCD remains incompletely understood, necessitating further investigation.
Conclusions:
- ASD and OCD exhibit shared genetic underpinnings and some overlapping cognitive features like inflexibility.
- Neuroimaging and cognitive assessments reveal distinct patterns, suggesting unique underlying mechanisms despite clinical overlap.
- Further research focusing on quantitative traits is crucial to elucidate the complex relationship between ASD and OCD.
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