Related Experiment Video
Updated: Sep 17, 2025
04:37
Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
948
Orthopedic Device Infections in Children.
Sandra R Arnold1, Joshua Wolf2
1Department of Pediatrics, Division of Infectious Diseases, University of Tennessee Health Science Center, Memphis, TN, USA; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Infectious Disease Clinics of North America
|June 27, 2025
Summary
Pediatric orthopedic device infections, particularly those involving spinal hardware and limb-salvage prostheses, require specialized diagnosis and management due to unique patient factors. Understanding these pediatric-specific challenges is crucial for improving treatment outcomes.
Area of Science:
- Pediatric Orthopedics
- Infectious Diseases
- Oncology
Background:
- Orthopedic device infections in children present unique challenges.
- These infections often occur in patients with complex comorbidities like neuromuscular disorders or solid tumors.
- Management requires a specialized, individualized approach.
Purpose of the Study:
- To review infections associated with spinal hardware in pediatric patients.
- To examine infections related to prostheses used in limb-salvage surgery for pediatric bone tumors.
- To highlight key differences in pediatric orthopedic device infections compared to adults.
Main Methods:
- Literature review focusing on pediatric orthopedic device infections.
- Analysis of patient characteristics, epidemiology, and management strategies.
- Comparison of pediatric and adult infection profiles.
Main Results:
- Pediatric orthopedic device infections are complex and diverse.
- Specific considerations for spinal hardware and limb-salvage prostheses in children were identified.
- Differences in patient factors, epidemiology, and management between pediatric and adult populations are significant.
Conclusions:
- Optimizing patient care and outcomes necessitates a thorough understanding of pediatric-specific orthopedic device infections.
- Specialized knowledge is vital for diagnosing and managing these complex cases in children.
- Further research into pediatric-specific treatment protocols is warranted.
Related Concept Videos
01:29Endocarditis IV: Nursing Management
40
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
40
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.4K
01:22Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
01:30Bacterial Signaling
34.5K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
34.5K
01:25Endocarditis I: Introduction
32
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
32
01:26Factors Affecting the Risk of Infection
12.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.3K