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![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Visible-Light-Promoted Copper-Catalyzed Etherification of Aryl Bromides via Energy Transfer
Xiantong Yao1, Ruiyuan Peng2, Xin Yang1
1School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China.
Abstract:
A visible-light-promoted copper-catalyzed C-O coupling reaction of alcohols with aryl bromides using eosin Y as the photosensitizer has been developed, in which energy transfer (EnT) from eosin Y to the copper complex of the oxalamide ligand generates an excited-state copper complex that facilitates oxidative addition of aryl bromides. This mild method enables the efficient synthesis of alkyl aryl ethers and biaryl ethers with a broad substrate scope and excellent tolerance of sensitive functional groups at room temperature.
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