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Myospasm and Fasciculation After Botulinum Toxin Injection
Aesthetic Surgery Journal. Open Forum
|July 2, 2025
Summary
Botulinum toxin type A (BTA) injections can rarely cause temporary dystonia. Careful injection techniques, like microdroplets, may help prevent this rare adverse effect.
Area of Science:
- Neurology
- Cosmetic Dermatology
Background:
- Botulinum toxin type A (BTA) is a common treatment for dystonia.
- Paradoxical dystonia induced by BTA injections is infrequently reported.
Observation:
- This case study retrospectively analyzed three patients who developed dystonia after cosmetic BTA injections.
- Symptoms included transient muscle spasms and abnormal contractions.
- Injection techniques such as microdroplet and intradermal methods were examined.
Findings:
- All patients experienced temporary dystonia, which resolved spontaneously or with minimal intervention.
- Microdroplet techniques and meticulous injection strategies appear to reduce the risk of BTA-induced dystonia.
- Potential causes include neurological injury, neuromuscular junction effects, uneven drug distribution, or denervation/recovery imbalances.
Implications:
- Modified BTA injection practices, including dosage, site distribution, and volume adjustments, can mitigate the risk of iatrogenic dystonia.
- Awareness of these rare adverse events is crucial for practitioners.
- Further research into the precise mechanisms causing BTA-induced dystonia is warranted.
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