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Contrast-Enhanced Mammography-Guided Biopsy: A Step-by-Step Guide
Olena O Weaver1, Wendie A Berg2
1Department of Breast Imaging, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1350, Houston, TX 77030.
AJR. American Journal of Roentgenology
|July 2, 2025
Summary
Contrast-enhanced mammography (CEM) guided biopsy is an emerging technique for suspicious breast lesions. Further optimization is needed to maximize its utility in clinical workflows.
Area of Science:
- Radiology
- Breast Imaging
- Interventional Radiology
Background:
- Contrast-enhanced mammography (CEM) is increasingly used diagnostically as an alternative to breast MRI.
- CEM-guided biopsy is a developing stereotactic approach for sampling enhancing lesions identified on CEM.
- Direct CEM-guided biopsy is becoming integral to efficient CEM procedures.
Purpose of the Study:
- To explore the current status of CEM-guided biopsy.
- To summarize indications, techniques, and practical tips for CEM-guided biopsy.
- To highlight areas for future optimization in CEM-guided biopsy procedures.
Main Methods:
- Literature review of existing studies on CEM-guided biopsy.
- Analysis of authors' clinical experience with CEM-guided biopsy.
- Exploration of technical aspects, including imaging and targeting.
Main Results:
- CEM-guided biopsy is a viable method for suspicious enhancing lesions.
- Practical guidance, troubleshooting, and alternative approaches are discussed.
- Further development is required to enhance imaging and targeting quality.
Conclusions:
- CEM-guided biopsy is an essential component of CEM workflows.
- Optimization efforts are needed from clinicians and vendors.
- Maximizing CEM-guided biopsy utility will enhance the overall value of CEM.
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