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MINFLUX: μs and nm precision 3D tracking of dynamic lipid mobility on nanoparticles
Laurence W Fitzpatrick1, Laura Woythe1, Ziqiang Huang2
1Department of Biomedical Engineering, Institute of Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands. L.albertazzi@tue.nl.
Nanoscale
|July 3, 2025
Abstract:
MINFLUX microscopy opened unique opportunities to investigate complex molecular systems at a single molecule level with μs temporal and nm spatial resolutions in 3D. Here, we demonstrate its use for the characterization of nanomaterials, providing a framework for MINFLUX imaging and data analysis tailored to understanding the complex dynamics of nanosized Silica-Supported Lipid Bilayers (SSLBs).
