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Prevention of non-invasive ventilation injuries in preterm infants: a systematic review

João Emanuel Pereira Domingos1, Ana Raquel Bezerra Saraiva Tavares1, Vanusa Maria Gomes Napoleão Silva1

  • 1Universidade Estadual do Ceará. Centro de Ciências da Saúde. Programa de Pós-Graduação em Cuidados Clínicos em Enfermagem e Saúde (PPCCLIS). Fortaleza, Ceará, Brasil.

Revista Gaucha De Enfermagem
|July 3, 2025
PubMed

Insights

Systemic rotation of masks and nasal prongs, with a hydrocolloid barrier, effectively prevents pressure injuries in preterm infants on noninvasive ventilation. This strategy ensures safe and high-quality neonatal care.

Area of Science:

  • Neonatal care
  • Medical device-related complications
  • Preventive medicine

Background:

  • Pressure injuries are a significant concern for preterm newborns requiring noninvasive ventilation.
  • Existing evidence on preventive strategies for these injuries is limited.

Purpose of the Study:

  • To systematically review scientific evidence on preventing pressure injuries in preterm infants using noninvasive ventilation.
  • To identify effective preventive care interventions.

Main Methods:

  • A systematic literature review of randomized controlled trials was conducted across multiple databases.
  • Studies were assessed for methodological quality and risk of bias using established tools.

Main Results:

  • Nine high-quality randomized clinical trials (2010-2021) were identified, all with low risk of bias.
  • The studies focused on interventions to mitigate pressure injuries associated with noninvasive ventilation devices.

Conclusions:

  • Systemic rotation between mask and nasal prongs, combined with a hydrocolloid protective barrier, is a priority intervention.
  • Integrating skin integrity checks and proper humidification enhances the safety and effectiveness of this preventive strategy.
Abstract

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