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Published on: August 30, 2019
Liver injury: What you need to know
Christopher R Reed1, Joshua B Brown, Andrew B Peitzman
1From the Department of Surgery, University of Pittsburgh School of Medicine (C.R.R.), Pittsburgh, Pennsylvania; Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh Medical Center (J.B.B.); and Department of Surgery (A.B.P.), University of Pittsburgh.
Nonoperative management is effective for most blunt liver injuries, decreasing mortality. However, severe liver trauma (grades IV-V) still presents significant operative challenges and risks, necessitating advanced surgical strategies.
Area of Science:
- Trauma Surgery
- Hepatobiliary Surgery
- Surgical Anatomy
Background:
- Liver injuries are common abdominal solid organ injuries.
- Grades I-III injuries are most frequent, while grades IV-V represent 12-20% of cases.
- Nonoperative management (NOM) is successful in 85-90% of hemodynamically stable blunt liver injuries.
Purpose of the Study:
- To review diagnostic, resuscitation, and triage considerations for liver trauma.
- To discuss limitations and complications of NOM and angioembolization.
- To present operative strategies for severe liver injuries.
Main Methods:
- Review of critical surgical anatomy and grading systems for liver trauma.
- Evaluation of diagnostic and resuscitation protocols.
- Analysis of nonoperative management, angioembolization, and surgical techniques for severe injuries.
Main Results:
- NOM has decreased overall mortality for blunt liver injury.
- Advances have not significantly reduced morbidity/mortality for grades IV-V injuries.
- Angioembolization is effective but carries risks like hepatic necrosis and sepsis.
Conclusions:
- NOM is the standard for stable blunt liver injuries.
- Severe liver injuries (grades IV-V) require specialized operative management.
- The "6 Ps" strategy is proposed for surgical hemorrhage control in severe liver trauma.
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