Peters' anomaly in association with ring 21 chromosomal abnormality

A white boy, born at the gestational age of 39 weeks, had Peters' anomaly in association with a ring 21 chromosomal abnormality. Dysmorphic features included low-set ears, hypoplastic mandible, delicate, dry skin, narrow arched palate, wide spaced nipples and hypotonia. He also had a cloudy right cornea. Chromosomal analysis disclosed a ring 21 defect. The cornea had a paracentral white opacity with a loss of posterior stroma and no adherence of the iris to the leukoma. Intraocular pressure, the lens, and the posterior pole were normal.