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Neuritis Ossificans in the Facial Nerve: A Case Report
Alyssa J Snyder1,2, Keven Seung Yong Ji2, Matthew D Wood3
1Albany Medical College, NY, USA.
The Annals of Otology, Rhinology, and Laryngology
|July 7, 2025
Summary
This report details the first case of neuritis ossificans, a rare nerve ossification, affecting the facial nerve (CN VII). Histopathology confirmed the diagnosis, leading to static suspension surgery for irreversible paralysis.
Area of Science:
- Neurology
- Pathology
- Ophthalmology
Background:
- Neuritis ossificans is a rare condition characterized by heterotopic ossification of nerves.
- It typically affects major peripheral nerves, with limited documentation involving cranial nerves.
Purpose of the Study:
- To report the first documented case of neuritis ossificans involving the facial nerve (CN VII).
- To review the clinical, radiologic, and histologic findings associated with this rare condition.
Main Methods:
- A case report of an 88-year-old male with progressive facial weakness following radiation therapy.
- Diagnostic procedures included MRI and facial nerve exploration with histopathological biopsy.
- Literature review of neuritis ossificans cases.
Main Results:
- Histopathology confirmed neuritis ossificans, revealing mineral deposits and absence of malignancy.
- The patient presented with complete flaccid paralysis of the right facial nerve.
- Nerve transfers were not feasible due to extensive nerve damage.
Conclusions:
- This is the first reported case of neuritis ossificans affecting the facial nerve.
- Diagnosis presented a significant challenge, underscoring the importance of histopathological evaluation.
- Static suspension surgery was chosen due to irreversible nerve paralysis.
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