Related Experiment Video

Updated: Apr 9, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

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α-Synuclein-Assembled Synaptic Vesicle Pools at the Presynaptic Terminal: A Study of α-Synuclein Function Using a

Chigure Suzuki1,2,3, Junji Yamaguchi1,4, Isei Tanida1

  • 1Department of Cellular and Molecular Neuropathology, Research Institute for Old Age, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.

Acta Histochemica Et Cytochemica
|July 9, 2025
PubMed
Summary

Alpha-synuclein (SNCA) is linked to Parkinson's disease. New research using transgenic mice reveals its role in synaptic vesicle formation at presynaptic terminals without causing motor deficits or neurodegeneration.

Keywords:
in-resin CLEMmKate2synaptic vesicle pooltransgenic mouseα-synuclein

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