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Updated: Sep 16, 2025

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
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Published on: June 30, 2021

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How hosts accurately command bacteria for gut health

Jianglin Zhang1, Xianda Ma1, Zheng Kuang1

  • 1Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

Cell Host & Microbe
|July 10, 2025
PubMed
Summary

Host APOL proteins selectively interact with Bacteroidales microbes. This interaction triggers outer membrane vesicle release, promoting gut immune homeostasis and mutualism.

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