Related Experiment Video
Updated: Sep 16, 2025
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Home-based collaborative management of bullous pemphigoid with delayed seropositive conversion of anti-BP180-NC16a
Hiromitsu Yamashita1, Takayuki Ando2, Hirohisa Fujikawa2,3
1Kawakita Family Clinic Minamiasagaya Tokyo Japan.
Abstract:
We report the case of an 82-year-old male with a history of multiple cerebral infarctions who developed bullous pemphigoid while receiving home-based care. Anti-BP180-NC16a antibody was initially negative, but later became positive as the disease severity worsened. The patient was successfully managed at home through a collaborative effort between a home-visiting physician (general practitioner), dermatologist, nursing staff, and pharmacists. This case highlights the value of reevaluating anti-BP180-NC16a antibody levels and the feasibility of home-based care for severe bullous pemphigoid in bedridden patients.
