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Updated: Sep 16, 2025

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
Published on: December 9, 2022
Global Trends and Developments in Diet and Longevity Research: A Bibliometric Analysis
Simge Sipahi1, Kezban Esen Karaca Çelik2, Nurhan Doğan3
1Department of Nutrition and Dietetics, Faculty of Health Sciences, Acibadem Mehmet Ali Aydinlar University, 34752 Istanbul, Turkey.
Abstract:
Background/Objectives: The global population is rapidly aging, raising interest in dietary practices for promoting the healthspan. This study aimed to comprehensively investigate the state of diet and longevity research over the past decade, addressing the lack of bibliometric synthesis within the field. Methods: A bibliometric analysis was performed using the keywords "diet" and "longevity" on English-language articles from the Web of Science database that were published from 2015 to 2024. Data were analyzed using Web of Science tools, InCites, and VOSviewer to identify trends in publication output, citation metrics, coauthorship networks, institutional contributions, and keyword co-occurrence patterns. Results: Overall, 2203 articles meeting the inclusion criteria were included in the analysis. Publication volume and citation counts gradually increased, peaking in 2021. Countries, including the United Kingdom, and organizations, such as the National Institutes of Health and Harvard University, had significant citation impact, and the United States and China led productivity. Molecular processes (oxidative stress and autophagy), dietary models (Mediterranean diet and calorie restriction), and public health issues (obesity and mortality) were the main thematic clusters. Model species, including Caenorhabditis elegans and Drosophila melanogaster, were frequently used. Regional disparities in research production and notable terminology variability were noted. Conclusions: This study emphasizes the development and diversity of nutrition and longevity research while highlighting novel molecular and translational topics. More international cooperation, uniform language, and multidisciplinary frameworks are warranted to promote equal scientific advancement worldwide and connect mechanistic discoveries with therapeutic outcomes.
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