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Serial Two-Photon Tomography of the Whole Marmoset Brain for Neuroanatomical Analyses
Published on: January 17, 2025
A Cross-Species Brain Magnetic Resonance Imaging and Histology Database of Vertebrates
Tomokazu Tsurugizawa1,2,3, Yuji Komaki4, Illia Aota5
1National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Abstract:
Understanding brain evolution requires detailed comparative analyses of brain structures across species. However, high-resolution anatomical and connective data remain limited for most vertebrates beyond a few well-studied model organisms. To address this gap, we collected postmortem brain samples from a range of vertebrates, primarily small amniotes, and performed magnetic resonance imaging and histological staining. Here, we present the "Animal Brain Collection (ABC)," a freely accessible database that enables researchers to examine and compare cellular and tissue-level brain architectures across species. This resource provides a foundation for cross-species investigations of brain structure and development, offering new opportunities for research into the diversity and evolution of vertebrate brains.

