Primary seminal vesicle adenocarcinoma in a squirrel monkey (Saimiri sciureus)

Area of Science:

• Veterinary Pathology
• Comparative Oncology
• Primate Medicine

Background:

• Primary seminal vesicle adenocarcinoma (PSVA) is a rare malignancy.
• Documented cases of PSVA are primarily in laboratory rodents.
• Neoplasms in non-human primates offer insights into comparative oncology.

Purpose of the Study:

• To report a case of primary seminal vesicle adenocarcinoma (PSVA) in a squirrel monkey.
• To describe the histopathological and immunohistochemical findings of this rare tumor.
• To contribute to the understanding of PSVA in new-world monkeys.

Main Methods:

• Clinical case presentation of a squirrel monkey with hematuria and emaciation.
• Gross and histopathological examination of the seminal vesicle tumor.
• Immunohistochemical analysis for cytokeratin and vimentin expression.

Main Results:

• A 22-year-old male squirrel monkey presented with symptoms of hematuria and emaciation.
• Autopsy revealed a solid mass in the seminal vesicle with ductal/papillary and solid patterns.
• Immunohistochemistry showed cytokeratin-negative tumor cells and vimentin-positive ductal/papillary cells.

Conclusions:

• The diagnosis of primary seminal vesicle adenocarcinoma (PSVA) was confirmed based on histopathology and tumor site.
• This represents a rare occurrence of PSVA in a new-world monkey.
• The findings aid in comparative oncology research and veterinary diagnostics.