Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Studies01:26

Longitudinal Studies

248
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
248
Longitudinal Research02:20

Longitudinal Research

12.5K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.5K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

52
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
52
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

37
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
37
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

35
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
35
Introduction to Epidemiology01:26

Introduction to Epidemiology

1.0K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incorporating ambient air pollution as a risk factor for tuberculosis mortality in Delhi, India.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

World Stroke Organization (WSO) rehabilitation certification program.

International journal of stroke : official journal of the International Stroke Society·2026
Same author

Cultural adaptation and psychometric validation of the Health Literacy Instrument for Adults with Tuberculosis (HELIA-TB) in India.

PloS one·2026
Same author

Phenotyping of Patients With Clinical Features of Advanced Heart Failure: A Latent Class Analysis of a Multicenter Registry of Patients Hospitalized With Heart Failure.

Journal of the American Heart Association·2026
Same author

Effectiveness and implementation of a primary healthcare intervention for multimorbidity and frailty among urban older adults in India: Protocol for the Multi-FrAME cluster randomized trial.

PloS one·2026
Same author

Overweight/obesity clustering and wealth differentials among indigenous households in Eastern India.

Scientific reports·2026

Related Experiment Video

Updated: Sep 15, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

587

Multiple Long-Term Conditions, Co-Long-Term Conditions and Polyvascular Disease: Considerations for Evidence

Gillian Mead1, Alex Todhunter-Brown2, Ukachukwu Abaraogu3,4

  • 1Usher Institute, University of Edinburgh Edinburgh UK.

Cochrane Evidence Synthesis and Methods
|July 14, 2025
PubMed
Summary

This article introduces

More Related Videos

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.6K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.5K

Related Experiment Videos

Last Updated: Sep 15, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

587
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.6K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts
08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.5K

Area of Science:

  • Medical Research
  • Systematic Reviews
  • Public Health

Background:

  • Cochrane's 2025-2030 strategy prioritizes improving lives of individuals with multiple chronic conditions.
  • Existing systematic reviews may not adequately address the complexities of multiple long-term conditions.

Purpose of the Study:

  • To explore considerations for multiple chronic conditions in systematic reviews.
  • To propose the term 'co-long-term conditions' to replace 'comorbidity'.
  • To define 'polyvascular disease' within the context of systematic reviews.

Main Methods:

  • Literature review and expert discussion by the Cochrane Thematic Group in Heart, Stroke and Circulation.
  • Analysis of current practices in systematic reviews concerning multiple long-term conditions.
  • Development of recommendations for review authors.

Main Results:

  • The term 'co-long-term conditions' is proposed for clarity.
  • Guidance is offered on defining 'polyvascular disease'.
  • Specific recommendations are made for data extraction, subgroup analyses, and discussion sections in systematic reviews.

Conclusions:

  • Systematic reviews should explicitly address co-long-term conditions.
  • Enhanced methodology will improve the representation of individuals with multiple conditions in research.
  • This approach is crucial for reviews on heart, circulatory, and stroke diseases, including polyvascular disease.