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Updated: Sep 15, 2025

Author Spotlight: Discovering New Alkaloids in Plants with Advanced Mass Spectrometry Techniques
Published on: March 8, 2024
Four new alkaloids from Dactylicapnos grandifoliolata
Xin-Yu Liu1,2, Jing Wu2, Feng Wei2
1School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China.
Abstract:
The first phytochemical investigation on D. grandifoliolata yielded twenty-four alkaloids, including four new ones, N-butylacetamide magnococline (1), fumariflorine methyl ester (6), (R)-corydalisol-2β-N-oxide (9), and (R)-coryximine-2α-N-oxide (10). Among them, compound 1 was an N-butylacetamide-substituted benzylisoquinoline alkaloid. Compounds 9 and 10 were N-oxides of benzylisoquinoline alkaloids. The structures of the new alkaloids were determined through comprehensive spectroscopic analysis and ECD calculations.
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