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Updated: Sep 15, 2025

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Intracranial Pressure Monitoring In Nontraumatic Intraventricular Hemorrhage Rodent Model
Published on: February 8, 2022
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Dynamic intraoperative changes in intracranial pressure during venous stenting.
Christopher H Sollenberger1, Albert Q Wu1, Kyle W Scott1
1Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Journal of Neurointerventional Surgery
|July 14, 2025
Summary
Idiopathic intracranial hypertension (IIH) can cause vision loss due to transverse sinus stenosis. Venous stenting, guided by intracranial pressure monitoring, offers a potential treatment for complex cases.
Area of Science:
- Neurology
- Neurosurgery
- Vascular Surgery
Background:
- Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure (ICP) without a clear cause.
- Transverse sinus stenosis is increasingly recognized as a contributing factor to IIH, leading to symptoms like vision loss and papilledema.
- Conservative management with acetazolamide may provide only transient relief for some patients.
Purpose of the Study:
- To report a case of successful venous sinus stenting in a patient with IIH and complex transverse sinus stenosis.
- To highlight the utility of intraoperative dynamic ICP monitoring in guiding the intervention.
- To demonstrate the feasibility of treating complex venous sinus stenoses with advanced angioplasty and stenting techniques.
Main Methods:
- A middle-aged female with IIH and progressive vision loss underwent evaluation for bilateral transverse sinus stenosis.
- Initial treatment with acetazolamide was followed by lumbar drainage and venous stenting due to recurrent symptoms and elevated ICP.
- Intraoperative dynamic ICP monitoring guided balloon angioplasty and stent deployment in the left transverse/sigmoid sinus, overcoming challenges of venous tortuosity and limited access.
Main Results:
- Successful balloon angioplasty and stent deployment were achieved despite technical difficulties.
- Post-intervention ICP measurements indicated improvement.
- The procedure resulted in improved clinical outcomes for the patient.
Conclusions:
- Dynamic ICP monitoring is crucial for guiding venous stenting in IIH patients.
- Refined treatment strategies utilizing advanced stenting techniques can effectively manage complex venous sinus stenoses.
- This approach holds promise for improving clinical outcomes in challenging IIH cases.
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