Related Experiment Video
Updated: Sep 15, 2025
08:42
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
3.6K
Complex Tricuspid and Pulmonic Carcinoid Heart Disease With Timely Surgical Repair
John Hollowed1, Hawkin Woo2, Solomon Hamburg3
1Division of Cardiology, University of California, Los Angeles, Los Angeles, California.
Texas Heart Institute Journal
|July 16, 2025
Summary
Surgical intervention improved quality of life for a patient with advanced carcinoid heart disease. Valve replacement offered substantial benefits for functional tolerance in this neuroendocrine tumor case.
Area of Science:
- Cardiology
- Oncology
- Gastroenterology
Background:
- Carcinoid heart disease (CHD) is a rare complication of neuroendocrine tumors (NETs).
- It typically involves the tricuspid and pulmonary valves, leading to significant morbidity.
- Early recognition and management are crucial for patient outcomes.
Observation:
- A 63-year-old male with hypertension, prediabetes, and sleep apnea presented with pedal edema, weight loss, and flushing.
- Elevated B-type natriuretic peptide and normocytic anemia were noted.
- Echocardiography revealed right ventricular enlargement and severe tricuspid regurgitation, suggestive of CHD.
Findings:
- Neuroendocrine tumor with liver metastasis was confirmed.
- Somatostatin therapy was ineffective, and symptoms were refractory to diuretics.
- Surgical valve replacement (tricuspid and pulmonary) resulted in significant improvement.
Implications:
- Surgical intervention is vital for advanced carcinoid heart disease.
- Valve replacement can substantially improve functional capacity and quality of life.
- This case underscores the multidisciplinary approach needed for managing complex NETs with cardiac involvement.
Related Concept Videos
01:26Mitral Stenosis III: Medical Management
27
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
27
01:29Cardiomyopathy V: Interprofessional Care
37
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
37