Optimising Paediatric Transition to Intensive Care for Adults (OPTICAL): study protocol for a mixed method study

Qi Huang1, Charmaine Kohn2, Sue Ben Abraham3

  • 1University College London Clinical Operational Research Unit, London, UK qi_huang@ucl.ac.uk.

BMJ Open
|July 16, 2025
PubMed

Insights

Improving intensive care unit (ICU) transitions for teenagers and young adults (TYA) with complex conditions is crucial. This study will analyze UK data and patient experiences to inform evidence-based policy for better TYA critical care.

Area of Science:

  • Critical Care Medicine
  • Health Services Research
  • Paediatric to Adult Transition

Background:

  • Teenagers and young adults (TYA) with chronic conditions face challenges transitioning to adult intensive care units (ICUs).
  • Existing adult ICU services are often ill-equipped for TYA, risking compromised care.
  • Current UK guidelines for ICU transition lack an evidence base, with limited established pathways.

Purpose of the Study:

  • To generate evidence for national policy on paediatric to adult ICU transition.
  • To improve clinical care and patient experience for TYA in ICUs.
  • To address the limitations of current, non-evidence-based transition recommendations.

Main Methods:

  • Mixed-methods study combining UK national data analysis (2017-2024) on ICU admissions and healthcare utilization.
  • Semistructured interviews, online forums, and surveys with TYA patients, carers, and health professionals.
  • Synthesis of evidence and stakeholder engagement to propose targeted improvements.

Main Results:

  • Analysis of UK national data (2017-2024) to identify clinical characteristics and healthcare resource utilization of TYA in ICUs.
  • Understanding of TYA and professional experiences of ICU transition through qualitative data collection.
  • Development of evidence-based recommendations for improving ICU transition pathways.

Conclusions:

  • This research will provide crucial evidence to inform national policy for TYA ICU transitions.
  • Findings aim to enhance the quality of care and patient experience during critical care.
  • The study addresses an urgent need for evidence-based guidelines in this specialized area of critical care.
Abstract