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Related Experiment Video

Updated: Sep 14, 2025

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice

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Complex Associations Between Pain and Masticatory Function in Patients With Muscular Temporomandibular Disorders.

Ta-Chung Chen1, Chia-Shu Lin2,3,4,5

  • 1Division of Prosthodontics, Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan.

Journal of Oral Rehabilitation
|July 21, 2025
PubMed
Summary

Temporomandibular disorders (TMD) patients experience eating difficulties but maintain adequate chewing ability. Treatment improved chewing performance and reduced pain, with severe pain linked to poorer chewing before therapy.

Keywords:
dietlongitudinal studiesmasticationpaintemporomandibular disorders

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Area of Science:

  • Oral health
  • Neurology
  • Rehabilitation

Background:

  • Previous research on temporomandibular disorders (TMDs) primarily addressed pain alleviation.
  • Deficits in masticatory function and the relationship between pain and mastication in TMD patients remain incompletely understood.

Purpose of the Study:

  • To investigate clinical pain and masticatory function in patients with muscular TMD.
  • To examine the associations between pain and mastication before and after treatment in muscular TMD patients.

Main Methods:

  • A comparative study involving 27 patients with muscular TMD and 27 healthy controls, matched for age, sex, and missing teeth.
  • Assessment of subjective eating experiences, adaptive eating strategies, and objective masticatory performance.
  • Evaluation of current pain and muscle pain in TMD patients pre- and post-treatment.

Main Results:

  • Muscular TMD patients reported greater eating difficulty and used more adaptive strategies, yet had comparable masticatory performance to controls before treatment.
  • Post-treatment, TMD patients showed improved masticatory performance and reduced pain.
  • Pre-treatment pain severity correlated with poorer masticatory performance in TMD patients.

Conclusions:

  • Patients with muscular TMD exhibit impaired masticatory experience but adequate performance.
  • Treatment positively impacts masticatory performance and pain levels.
  • Pre-treatment pain is a significant factor associated with reduced masticatory performance in TMD.