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Building a Broader Understanding of Enterotoxigenic Escherichia coli

David A Sack1, August L Bourgeois1, Subhra Chakraborty1

  • 1Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Open Forum Infectious Diseases
|July 21, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Bangladeshburdendiseaseenterotoxigenic E. coliepidemiology

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Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
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