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CAD-CAM Complete Removable Dental Prostheses: A Pilot Study Evaluating a Novel System Using a Bicolored Monolithic
The International Journal of Prosthodontics
|July 22, 2025
Summary
This pilot study found that monolithic digital complete dentures made from two-colored resin disks offer excellent esthetics and improved bite force. These CAD/CAM dentures are a promising treatment option for patients.
Area of Science:
- Dental Materials Science
- Prosthodontics
- Digital Dentistry
Background:
- Complete dentures are crucial for oral function and aesthetics.
- Traditional denture fabrication can be time-consuming and technique-sensitive.
- Digital workflows offer potential for improved efficiency and predictability in prosthodontics.
Purpose of the Study:
- To evaluate the esthetic and clinical outcomes of monolithic digital complete dentures.
- To assess dentures fabricated from two-colored, shell-geometry Polymethylmethacrylate (PMMA) disks.
- To explore patient-reported outcomes and prosthetic maintenance.
Main Methods:
- Utilized the Biofunctional Prosthetic System workflow for manufacturing complete dentures.
- Assessed primary outcome of esthetic appearance via pink-white transition accuracy and esthetic scores.
- Evaluated secondary outcomes including oral health-related quality of life (OHRQoL), denture satisfaction index (DSI), masticatory performance (MP), maximum bite force (MBF), and bite pressure (BP).
Main Results:
- Dentures fabricated from two-colored PMMA disks demonstrated high esthetic scores, surpassing previous dentures.
- Significant improvements were observed in maximum bite force (MBF) and bite pressure (BP) (p<0.05).
- Minor deviations in the white-pink transition were noted in some prostheses, but overall esthetics were positively received.
Conclusions:
- The two-colored shell-geometry resin disk design is suitable for CAD/CAM complete denture manufacturing, achieving favorable esthetics.
- The novel digital denture system shows potential as a viable treatment modality with positive patient-reported and clinical outcomes.
- Further research is warranted to validate these findings in larger cohorts.

