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Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report
Thuy Thanh Cavens1, Janneke de Vries2, Suzanne Verleisdonk-Bolhaar3
1Department of Pathology VieCuri, Tegelseweg 210, 5912 BL Venlo, Netherlands.
Abstract:
Cladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy revealed pigmented, septate hyphae without muriform cells, consistent with a diagnosis of phaeohyphomycosis. Surgical excision and culture confirmed C. boppii. Afterwards the patient received a three-week course of itraconazole, which led to infection resolution. This report and review of literature underscores the diagnostic and therapeutic approaches for managing deep cutaneous infections caused by C. boppii.
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