Globe Volume Asymmetry After Intra-arterial Chemotherapy for Retinoblastoma

Retinoblastoma, a potentially fatal pediatric intraocular malignancy, is now curable with intravenous and intra-arterial (IAC) chemotherapy. In this report, the authors describe globe volume asymmetry, a lesser-known sequela of IAC, as well as the hemodynamics of a tumor-laden eye, pattern of eyeball growth following IAC, and potential mechanisms of amblyopia in retinoblastoma survivors. [J Pediatr Ophthalmol Strabismus. 2025;62(4):e46-e50.].