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Deep Learning for Autonomous Surgical Guidance Using 3-Dimensional Images From Forward-Viewing Endoscopic Optical
Sinaro Ly1, Adrien Badré1, Parker Brandt1
1School of Computer Science, University of Oklahoma, Norman, Oklahoma, USA.
Journal of Biophotonics
|July 25, 2025
Summary
A novel three-dimensional convolutional neural network (3D-CNN) improves accuracy in analyzing optical coherence tomography (OCT) images for enhanced surgical guidance. This AI tool offers faster real-time performance compared to other advanced models.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Surgical Technology
Background:
- Percutaneous nephrostomy requires precise guidance for optimal outcomes.
- Volumetric optical coherence tomography (OCT) provides detailed anatomical information.
- Current image analysis methods may limit real-time surgical decision-making.
Purpose of the Study:
- To develop and evaluate a 3D-CNN for analyzing volumetric OCT images.
- To enhance endoscopic guidance during percutaneous nephrostomy procedures.
- To compare the performance of the 3D-CNN against 2D-CNNs and other state-of-the-art volumetric models.
Main Methods:
- A 3D-CNN was designed for volumetric OCT image analysis.
- Performance was assessed using 10-fold nested cross-validation on porcine kidney datasets.
- The 3D-CNN was benchmarked against 3D-ViT, 3D-DenseNet121, and M3T models.
Main Results:
- The 3D-CNN achieved an average test accuracy of 90.57%, outperforming 2D-CNN models (85.63%-88.22%).
- Inference latency for the 3D-CNN was 33 ms, significantly lower than competing volumetric architectures.
- Comparable inferencing accuracy was observed across the evaluated state-of-the-art models.
Conclusions:
- The developed 3D-CNN is a highly accurate and efficient tool for OCT image analysis.
- Its low inference latency makes it suitable for real-time applications in computer-aided diagnosis.
- This technology holds significant potential for improving OCT-guided surgical interventions.

