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The Effects of St. John's Wort on Healing of Stages 1 and 2 Pressure Injuries: A Randomized Controlled Trial
Sevinç Yıldırım1,2,3, Hatice Kaya1,2,3, Öner Süzer1,2,3
1Sevinç Yıldırım, PhD, Darulaceze Presidency, Istanbul, Turkey.
Purpose:
This purpose of this study was to evaluate the effects of topical St. John's wort (Hypericum perforatum) oil on wound healing in Stages 1 and 2 pressure injuries (PI).
Design:
Randomized controlled trial.
Methods:
The study was conducted between September 2020 and June 2021 in a nursing home in Istanbul, Turkey. The sample comprised 48 participants: 24 were randomly allocated to the intervention group and 24 individuals to the control group. The intervention was 0.9% NaCl and St. John's wort oil; 0.9% NaCl was administered to control group participants. The Pressure Ulcer Scale for Healing was used to measure wound healing.
Results:
No significant between-group differences were found when control and intervention groups were evaluated at weeks 1, 2, 3, or 4.
Conclusion:
The findings of this randomized controlled trial revealed no difference between wound healing outcomes when St' John's wort oil was compared to saline in a group of patients. We recommend additional research using various stages and categories of PI to more fully determine the potential effects of topical St. John's wort oil on PI healing.
