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Updated: Jun 19, 2026

Analysis of Embryonic and Larval Zebrafish Skeletal Myofibers from Dissociated Preparations
Published on: November 13, 2013
Zebrafish: Lessons and Insights into Skeletal Muscle Research
Yansong Lu1, Avnika A Ruparelia2,3,4, Peter D Currie2,5
1Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
None:
Recent technological advances in genome editing capabilities and live imaging capacities have greatly increased the use of the zebrafish model in skeletal muscle research, leading to critical discoveries in the cellular and molecular processes regulating skeletal muscle growth, regeneration, and disease. This is highlighted by the characterization of muscle stem cell and progenitor cell dynamics during growth, the visualization of novel cellular interactions driving regeneration, and the identification of complex disease mechanisms and potential therapies for muscle diseases. This review highlights these latest advancements and discuss the limitations and future directions of zebrafish in skeletal muscle research, focusing on muscle growth, regeneration, and disease.
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