Related Experiment Videos
[Etiology of intestinal Enterobacteriaceae infections in young children]
Abstract:
Enterobacteria, potentially capable of causing infections, were isolated from the feces of 88.7% of young children in the intestinal department of an infectious disease hospital. Opportunistic bacteria were considered to be the causative agents of infections only in cases of their high concentration in the material under test. In about a half of the cases the etiological role of the suspected microorganisms was confirmed by the detection of antibodies in low titers. The presence of maternal antibodies did not interfere with diagnostic procedures. The detection of antibodies to autocultures, even in a single case, is of diagnostic importance in the examination of young children. Autoserologically confirmed mixed infection was found to take a more prolonged course than autoserologically confirmed monoinfection.
Insights
Enterobacteria were common in young children hospitalized with intestinal issues. Detecting antibodies to these bacteria aids in diagnosing infections, especially mixed infections which prolong illness.
Area of Science:
- Microbiology
- Clinical Diagnostics
- Pediatrics
Context:
- Enterobacteria are frequently found in the gut microbiota of young children, particularly those in hospital settings with intestinal conditions.
- Identifying opportunistic bacteria as causative agents requires assessing their concentration and correlating with host immune response.
- The study focuses on children within an infectious disease hospital's intestinal department.
Purpose:
- To investigate the prevalence of Enterobacteria in hospitalized young children.
- To evaluate the diagnostic significance of antibody detection against Enterobacteria and autocultures in young children.
- To compare the clinical course of monoinfections versus mixed infections confirmed by autoserology.
Summary:
- Enterobacteria were isolated from 88.7% of young children in an infectious disease hospital's intestinal department.
- Antibody detection confirmed the etiological role of suspected microorganisms in approximately half of the cases, unaffected by maternal antibodies.
- Autoserologically confirmed mixed infections showed a more prolonged course compared to monoinfections.
Impact:
- Highlights the importance of Enterobacteria surveillance in pediatric infectious diseases.
- Establishes antibody detection to autocultures as a valuable diagnostic tool in young children.
- Provides insights into the clinical management and prognosis of bacterial infections in pediatric patients.