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Updated: Sep 13, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
An explainable artificial intelligence handbook for psychologists: Methods, opportunities, and challenges
Rosa Lavelle-Hill1, Gavin Smith2, Hannah Deininger3
1Digital Humanities Lab, University of Basel.
Abstract:
With more researchers in psychology using machine learning to model large data sets, many are also looking to eXplainable artificial intelligence (XAI) methods to understand how their model works and to gain insights into the most important predictors. However, the methodological approach for establishing predictor importance in a machine learning model is not as straightforward or as well-established as with traditional statistical models. Not only are there a large number of potential XAI methods to choose from, but there are also a number of unresolved challenges when using XAI to understand psychological data. This article aims to provide an introduction to the field of XAI for psychologists. We first introduce explainability from an applied machine learning perspective and contrast it to that in psychology. Then we provide an overview of commonly used XAI approaches, namely permutation importance, impurity-based feature importance, individual conditional expectation graphs, partial dependence plots, accumulated local effect graphs, Local Interpretable Model-agnostic Explanations (LIME), SHapley Additive exPlanations (SHAP), and Deep Learning Important FeaTures (DeepLIFT). Finally, we demonstrate the impact of multicollinearity on different XAI methods using a simulation analysis and discuss the implementation challenges and future directions in psychological research. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
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